Succinates
2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt
Quick view. We supply 2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt as a 2'-O-MOE adenosine succinate used to prepare nucleoside-loaded solid supports or terminally modified oligonucleotides. CAS 444814-78-2. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt is classified as oligonucleotide support or succinate intermediate (Formula C45H45N5O11; molecular weight 831.87).
2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Useful catalog search terms
- CAS 444814-78-2
- Oligonucleotide support or succinate intermediate
- 2'-O-MOE modification
- succinate linker
- Succinates
Physicochemical data
| Key chemistry motifs | 2'-O-MOE modification; succinate linker |
|---|---|
| Density | 1.338±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pKa | 4.374±0.17(predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
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Frequently asked questions
Can the package size for 2'-MOE-A(Bz) 3'-succinate, Triethylammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0012 and CAS 444814-78-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Succinates product family and its named chemistry.