Base-protected Nucleosides
N6-Benzoyl-2'-O-methyladenosine
Quick view. An N6-benzoyl-protected adenosine building block bearing a 2'-O-methyl substituent and free 3'- and 5'-hydroxyl groups. CAS 85079-00-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Benzoyl-2'-O-methyladenosine is classified as base-protected nucleosides (Formula C18H19N5O5; molecular weight 385.38).
N6-Benzoyl-2'-O-methyladenosine — Identity-defined, base-protected 2'-O-methyl nucleoside building block for research workflows involving nucleoside, nucleotide, and oligonucleotide chemistry.
For N6-Benzoyl-2'-O-methyladenosine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Me-rA(Bz)
- N6-Bz-2'-OMe-rA
- 2'-O-Methyl-N6-benzoyladenosine
Useful catalog search terms
- CAS 85079-00-1
Physicochemical data
| Systematic name | N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide |
|---|---|
| Nucleoside | Adenosine |
| Base protection | N6-Benzoyl |
| Sugar modification | 2'-O-Methyl |
| Free hydroxyl groups | 3' and 5' |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O |
| InChI | InChI=1S/C18H19N5O5/c1-27-14-13(25)11(7-24)28-18(14)23-9-21-12-15(19-8-20-16(12)23)22-17(26)10-5-3-2-4-6-10/h2-6,8-9,11,13-14,18,24-25H,7H2,1H3,(H,19,20,22,26)/t11-,13-,14-,18-/m1/s1 |
| InChIKey | PHFHSPQCDRKMQJ-XWXWGSFUSA-N |
| PubChem CID | 13852840 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe N6-Benzoyl-2'-O-methyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N6-Benzoyl-2'-O-methyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0107 and CAS 85079-00-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.