Base-protected Nucleosides
2'-O-propargyl-rC(Bz)
Quick view. We supply 2'-O-propargyl-rC(Bz) as a protected 2'-O-propargyl nucleoside intermediate for click-compatible oligonucleotide building blocks. CAS 210096-41-6. Catalog target purity: Specification on request.
Product profile
2'-O-propargyl-rC(Bz) is classified as nucleoside or protected nucleoside intermediate.
2'-O-propargyl-rC(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-O-propargyl-rC(Bz), copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Useful catalog search terms
- CAS 210096-41-6
- Nucleoside or protected nucleoside intermediate
- alkyne click handle
- Base-protected Nucleosides
Physicochemical data
| Key chemistry motifs | alkyne click handle |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe 2'-O-propargyl-rC(Bz) or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2',3'-dideoxy-C(Ac)
Base-protected Nucleosides · CAS: 119818-52-9
BX-PN-00032',3'-dideoxy-C(Bz)
Base-protected Nucleosides · CAS: 120885-60-1
BX-PN-00052'-F-dG(DMF)
Base-protected Nucleosides · CAS: N/A
BX-PN-00062'-O-4'-C-Locked-5-Me-rC(Bz)
Base-protected Nucleosides · CAS: 206055-81-4
BX-PN-00072'-O-4'-C-Locked-rC(Bz)
Base-protected Nucleosides · CAS: 221229-74-9
BX-PN-00092'-O-4'-C-Locked-rG(iBu)
Base-protected Nucleosides · CAS: 206055-68-7
Frequently asked questions
Can the package size for 2'-O-propargyl-rC(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0087 and CAS 210096-41-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-O-propargyl-rC(Bz) or the named structural feature represented by this product.