Succinates
2'-OMe-C(Ac)-3'-succinate
Quick view. We supply 2'-OMe-C(Ac)-3'-succinate as a 2'-O-methyl cytidine succinate used to prepare nucleoside-loaded solid supports or terminally modified oligonucleotides. CAS 2746380-46-9. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-OMe-C(Ac)-3'-succinate is classified as oligonucleotide support or succinate intermediate (Formula C37H39N3O11; molecular weight 701.72).
2'-OMe-C(Ac)-3'-succinate can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-OMe-C(Ac)-3'-succinate, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- CAS 2746380-46-9
- Oligonucleotide support or succinate intermediate
- 2'-O-methyl modification
- succinate linker
- Succinates
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification; succinate linker |
|---|---|
| Density | 1.320±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pKa | 4.374±0.17(predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-OMe-C(Ac)-3'-succinate or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
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BX-SUCC-0005DMTr-2'-F-dG(iBu)-3'-succinate, TEA salt
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Frequently asked questions
Can the package size for 2'-OMe-C(Ac)-3'-succinate be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0021 and CAS 2746380-46-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Succinates product family and its named chemistry.