Amino-modified Nucleosides
3'-NH₂-ddT
Quick view. We supply 3'-NH₂-ddT as a thymidine 3'-amino dideoxy analog used as a chain-terminating and derivatizable nucleoside. CAS 52450-18-7. Catalog target purity: ≥99%.
Product profile
3'-NH₂-ddT is classified as nucleoside or protected nucleoside intermediate (Formula C10H15N3O4; molecular weight 241.244).
3'-NH₂-ddT can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-NH₂-ddT, reported solubility: DMSO (Slightly, Heated), Methanol (Sparingly, Heated). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 3-AMT
- Whi-02
- Nsc620059
- Aids000909
- Ni 2-110-2
- 3’-aminothymidine
- 3Deoxy-3aminothymidine
- 3'-AMINO-3'-DEOXYTHYMIDINE
Useful catalog search terms
- CAS 52450-18-7
- Nucleoside or protected nucleoside intermediate
- Amino-modified Nucleosides
Physicochemical data
| Melting point | 161-1620C |
|---|---|
| Density | 1.360±0.06 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| Form | Powder |
| Color | Off-white to Yellow |
| SMILES | OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1N |
| InChI | InChI=1S/C10H15N3O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h,6-8,14H,2,4,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s |
| InChIKey | ADVCGXWUUOVPPB-XLPZGREQSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 3'-NH₂-ddT or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-NH₂-ddA
Amino-modified Nucleosides · CAS: 7403-25-0
BX-MN-00073'-NH₂-ddC
Amino-modified Nucleosides · CAS: 84472-90-2
BX-MN-00083'-NH₂-ddG
Amino-modified Nucleosides · CAS: 66323-49-7
BX-MN-01762-NH₂-rA
Amino-modified Nucleosides · CAS: 2096-10-8
BX-AMN-00026-Amino-4-methoxy-1-(2-deoxy-3,5-di-O-(p-toluoyl)--D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
Amino-modified Nucleosides · CAS: 100644-68-6
BX-AMN-01343'-beta-Azido-2',3'-dideoxyuridine
Amino-modified Nucleosides · CAS: 101039-96-7
Frequently asked questions
Can the package size for 3'-NH₂-ddT be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0009 and CAS 52450-18-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.