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BX LAB PRODUCT CATEGORY

2'-Fluoro Phosphoramidites

Quick view. 2′-fluoro nucleoside phosphoramidites for modified RNA, siRNA and stability-focused oligonucleotide studies. This category currently includes 22 products. 2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

Products22
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

How to select

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

How to qualify

Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.

Product-family considerations

Common advantages
  • Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
  • Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
  • Common ribose modifications can improve nuclease resistance and modulate RNA-like binding behavior.
Common limitations
  • Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
  • Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.

Category literature

These publications provide background for the 2'-Fluoro Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

22 products

Chemical structure of DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-PhosphoramiditeDMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite

≥95% · CAS: 2227139-97-9

BX-2FP-0022
Chemical structure of DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-PhosphoramiditeDMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite

≥95% · CAS: 1528733-99-4

BX-2FP-0023
Chemical structure of DMTr-2'-F-dU-3'-CE-PhosphoramiditeDMTr-2'-F-dU-3'-CE-Phosphoramidite

≥98.0% · CAS: 146954-75-8

BX-2FP-0024
Chemical structure of DMTr-2'-F-dC(Ac)-3'-CE-PhosphoramiditeDMTr-2'-F-dC(Ac)-3'-CE-Phosphoramidite

≥98.0% · CAS: 159414-99-0

BX-2FP-0025
Chemical structure of DMTr-2'-F-dA(Bz)-3'-CE-PhosphoramiditeDMTr-2'-F-dA(Bz)-3'-CE-Phosphoramidite

99% · CAS: 136834-22-5

BX-2FP-0026
Chemical structure of DMTr-2'-F-dG(iBu)-3'-CE-PhosphoramiditeDMTr-2'-F-dG(iBu)-3'-CE-Phosphoramidite

≥98.0% · CAS: 144089-97-4

BX-2FP-0027
Chemical structure of DMTr-2'-F-dC(Bz)-3'-CE-PhosphoramiditeDMTr-2'-F-dC(Bz)-3'-CE-Phosphoramidite

≥98% · CAS: 161442-19-9

BX-2FP-0028
Chemical structure of DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-PhosphoramiditeDMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite

≥98% · CAS: 1528734-00-0

BX-2FP-0002
Chemical structure of 2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite

≥98% · CAS: 2245842-16-2

BX-2FP-0021
Chemical structure of DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-PhosphoramiditeDMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite

≥98% · CAS: 2227140-01-2

BX-2FP-0007
Chemical structure of DMTr-2'-F-dT-3'-CE-PhosphoramiditeDMTr-2'-F-dT-3'-CE-Phosphoramidite

≥98% · CAS: 182700-06-7

BX-2FP-0009
Chemical structure of DMTr-2'-F-dU-3'-(D)-DPSE-PhosphoramiditeDMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite

≥98% · CAS: 1528734-09-9

BX-2FP-0010
Chemical structure of DMTr-2'-F-dU-3'-(L)-DPSE-PhosphoramiditeDMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite

≥98% · CAS: 1528734-08-8

BX-2FP-0011
Chemical structure of DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-PhosphoramiditeDMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite

≥98% · CAS: 3055727-89-1

BX-2FP-0012
Chemical structure of DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-PhosphoramiditeDMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite

≥98% · CAS: N/A

BX-2FP-0001
Chemical structure of DMTr-2'-F-dG(dmf)-3'-(L)-PSM-PhosphoramiditeDMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite

≥98% · CAS: N/A

BX-2FP-0005
Chemical structure of DMTr-2'-F-dG(dmf)-3'-CE-PhosphoramiditeDMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite

≥98% · CAS: 3081868-42-7

BX-2FP-0006
Chemical structure of DMTr-2'-F-dG(iBu)-3'-(L)-PSM-PhosphoramiditeDMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite

≥98% · CAS: N/A

BX-2FP-0008
Chemical structure of DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-PhosphoramiditeDMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite

≥98% · CAS: N/A

BX-2FP-0003
Chemical structure of DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-PhosphoramiditeDMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite

≥98% · CAS: N/A

BX-2FP-0004
Chemical structure of N4-benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramiditeN4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite

≥98% · CAS: 182495-83-6

BX-2FP-0032
Chemical structure of MMTr-2'-F-dG(iBu)-3'-CE phosphoramiditeMMTr-2'-F-dG(iBu)-3'-CE phosphoramidite

≥98% · CAS: N/A

BX-2FP-0014

Frequently asked questions

What are typical uses for 2'-Fluoro Phosphoramidites?

2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

What should be confirmed before ordering 2'-Fluoro Phosphoramidites?

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

Are custom quantities or related analogs available?

BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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