2'-F Nucleosides
2'-Fluoro-2'-deoxyadenosine
Quick view. 2'-Fluoro-2'-deoxyadenosine is a ribo-configured 2'-fluoro nucleoside building block for research-use modified-nucleoside and oligonucleotide chemistry. CAS 64183-27-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Fluoro-2'-deoxyadenosine is classified as 2'-fluoro nucleoside (Formula C10H12FN5O3; molecular weight 269.23).
A 2'-fluoro-2'-deoxyadenosine building block for research-use modified-nucleoside and oligonucleotide chemistry.
For 2'-Fluoro-2'-deoxyadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-F-dA
- 2'-Deoxy-2'-fluoro-D-adenosine
- Adenosine, 2'-deoxy-2'-fluoro-
Useful catalog search terms
- CAS 64183-27-3
Physicochemical data
| PubChem CID | 100253 |
|---|---|
| InChIKey | ZGYYPTJWJBEXBC-QYYRPYCUSA-N |
| Modification | fluorine at the ribose 2'-position |
| InChI | InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1 |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Fluoro-2'-deoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Fluoro-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0180 and CAS 64183-27-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.