Succinates
2'-MOE-G(iBu)-3'-succinate
Quick view. We supply 2'-MOE-G(iBu)-3'-succinate as a 2'-O-MOE guanosine succinate used to prepare nucleoside-loaded solid supports or terminally modified oligonucleotides. CAS 2622236-64-8. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-MOE-G(iBu)-3'-succinate is classified as oligonucleotide support or succinate intermediate.
2'-MOE-G(iBu)-3'-succinate can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-MOE-G(iBu)-3'-succinate, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Useful catalog search terms
- CAS 2622236-64-8
- Oligonucleotide support or succinate intermediate
- 2'-O-MOE modification
- succinate linker
- Succinates
Physicochemical data
| Key chemistry motifs | 2'-O-MOE modification; succinate linker |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 2'-MOE-G(iBu)-3'-succinate or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-SUCC-0003DMTr-2'-F-dA(Bz)-3'-succinate, TEA salt
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BX-SUCC-0004DMTr-2'-F-dC(Ac)-3'-succinate, TEA salt
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BX-SUCC-0005DMTr-2'-F-dG(iBu)-3'-succinate, TEA salt
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BX-SUCC-0006DMTr-2'-F-dU-3'-succinate, TEA salt
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Frequently asked questions
Can the package size for 2'-MOE-G(iBu)-3'-succinate be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUCC-0024 and CAS 2622236-64-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Succinates product family and its named chemistry.