Halogenated Nucleosides
3'-Deoxy-3'-fluoroadenosine
Quick view. We supply 3'-Deoxy-3'-fluoroadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 75059-22-2. Catalog target purity: Specification on request.
Product profile
3'-Deoxy-3'-fluoroadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12FN5O3; molecular weight 269.23).
3'-Deoxy-3'-fluoroadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-Deoxy-3'-fluoroadenosine, form: Solid.
Names and search terms
Confirmed or normalized name variants
- 3'-Fluoro-3'-deoxyadenosine
- 3'-F-3'-rA
- Adenosine, 3'-deoxy-3'-fluoro-
- (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
Useful catalog search terms
- CAS 75059-22-2
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s |
|---|---|
| InChIKey | QCDAWXDDXYQEJJ-QYYRPYCUSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1F |
| Melting point | 211-212 °C |
| Boiling point | 628.6±65.0 °C(Predicted) |
| Density | 2.01±0.1 g/cm3(Predicted) |
| pKa | 12.45±0.70(Predicted) |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-5-CF3-dU
Halogenated Nucleosides · CAS: 70-00-8
BX-HN-00026-Cl-purine-2'-deoxyriboside
Halogenated Nucleosides · CAS: 4594-45-0
BX-HN-00038-Cl-2'-dA
Halogenated Nucleosides · CAS: 85562-55-6
BX-HN-00042'-Chloro-2'-deoxycytidine
Halogenated Nucleosides · CAS: 10212-19-8
BX-HN-00055-bromo-2'-deoxycytidine
Halogenated Nucleosides · CAS: 1022-79-3
BX-HN-00065-Iodouridine
Halogenated Nucleosides · CAS: 1024-99-3
Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluoroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0251 and CAS 75059-22-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.