Halogenated Nucleosides
5'-Deoxy-5'-iodoadenosine
Quick view. We supply 5'-Deoxy-5'-iodoadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 4099-81-4. Catalog target purity: ≥95%.
Product profile
5'-Deoxy-5'-iodoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12IN5O3; molecular weight 377.14).
5'-Deoxy-5'-iodoadenosine — Important precursors for the synthesis of nucleotides, sugar nucleosides and as biologically active substances
For 5'-Deoxy-5'-iodoadenosine, storage: −20 °C. Form: Solid.
Names and search terms
Confirmed or normalized name variants
- 5'-iodoadenosine
- 5'-IODO-5'-DEOXYADENOSINE
- 5''-DEOXY-5''-JOD-ADENOSINE
- 5'-Deoxy-5'-iodo-D-adenosine
Useful catalog search terms
- CAS 4099-81-4
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| Melting point | 178–187 °C |
|---|---|
| SMILES | Nc1ncnc2c1ncn2C1OC(CI)C(O)C1O |
| InChIKey | FUWWLIOFNXNKQR-KQYNXXCUSA-N |
| InChI | InChI=1S/C10H12IN5O3/c11-1-4-6(17)7(18)10(19-4)16-3-15-5-8(12)13-2-14-9(5)16/h2-4,6-7,10,17-18H,1H2,(H2,12,13,14)/t4-,6-,7-,10-/m1/s |
| Boiling point | 671.1±65.0 °C(Predicted) |
| Density | 1.7865 (estimate) |
| pKa | 13.03±0.70(Predicted) |
| Form | Solid |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5'-Deoxy-5'-iodoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-Deoxy-5'-iodoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0118 and CAS 4099-81-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.