Nucleosides & Deoxynucleosides
5-Me-rC
Quick view. We supply 5-Me-rC as 5-methylcytidine, a natural RNA modification and synthetic intermediate. CAS 2140-61-6. Catalog target purity: Specification on request.
Product profile
5-Me-rC is classified as nucleoside or protected nucleoside intermediate (Formula C10H15N3O5; molecular weight 257.24).
5-Me-rC can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Me-rC, reported solubility: DMSO (Slightly), Methanol (Slightly), Water (Sparingly). Storage: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C.
Names and search terms
Confirmed or normalized name variants
- 5-METHYLCYTIDINE
- 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidin-2-one
Useful catalog search terms
- CAS 2140-61-6
- Nucleoside or protected nucleoside intermediate
- Nucleosides & Deoxynucleosides
Physicochemical data
| Melting point | 212-215 °C (dec.) (lit.) |
|---|---|
| Boiling point | 537.5±60.0 °C(Predicted) |
| Density | 1.79 |
| pKa | pK1:4.21 (25°C) |
| Form | Solid |
| Color | Off-White to Pale Beige |
| SMILES | OC[C@H]1O[C@@H](N2C=C(C)C(N)=NC2=O)[C@H](O)[C@@H]1O |
| InChI | InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s |
| InChIKey | ZAYHVCMSTBRABG-JXOAFFINSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Me-rC be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-NDO-0021 and CAS 2140-61-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Nucleosides & Deoxynucleosides product family and its named chemistry.