Nucleosides & Deoxynucleosides
Alovudine
Quick view. We supply Alovudine as a fluorinated nucleoside analog historically studied as an antiviral/antiretroviral compound and biochemical reference. CAS 25526-93-6. Catalog target purity: Specification on request.
Product profile
Alovudine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13FN2O4; molecular weight 244.22).
Alovudine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For Alovudine, reported solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly). Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere.
Names and search terms
Confirmed or normalized name variants
- FLT
- MIV 310
- CL 184824
- NSC 140025
- 3'-FLUOROTHYMIDINE
- 3'-FLUORODEOXYTHYMIDINE
- Fms-like tyrosine kinase 1
- 3'-DEOXY-3'-FLUOROTHYMIDINE
Useful catalog search terms
- CAS 25526-93-6
- Nucleoside or protected nucleoside intermediate
- Nucleosides & Deoxynucleosides
Physicochemical data
| Melting point | 176-178 °C(lit.) |
|---|---|
| Density | 1.2866 (estimate) |
| pKa | 9.55±0.10(Predicted) |
| Color | White to Beige |
| SMILES | O=C1NC(C(=CN1[C@H]1C[C@@H]([C@H](O1)CO)F)C)=O |
| InChI | InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s |
| InChIKey | UXCAQJAQSWSNPQ-XLPZGREQSA-N |
| Form | buffered aqueous solution |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for Alovudine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-NDO-0015 and CAS 25526-93-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Nucleosides & Deoxynucleosides product family and its named chemistry.