Intermediates
Amino-PEG8-t-Boc-hydrazide
Quick view. Amino-PEG8-t-Boc-hydrazide is a bifunctional PEG linker intermediate identified by CAS 1334169-96-8. CAS 1334169-96-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
Amino-PEG8-t-Boc-hydrazide is classified as intermediates (Formula C24H49N3O11; molecular weight 555.67).
Amino-PEG8-t-Boc-hydrazide — Reference use: PEG linker assembly involving an amino terminus and a Boc-protected hydrazide terminus.
For Amino-PEG8-t-Boc-hydrazide, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- Amino-PEG8-hydrazide-Boc
- NH2-PEG8-HZ-Boc
- AxisPharm AP12184
Useful catalog search terms
- CAS 1334169-96-8
- C24H49N3O11
- GKXIUVNZWFPOHI-UHFFFAOYSA-N
- PubChem CID 75535022
Physicochemical data
| Functional groups | Amine and Boc-protected hydrazide |
|---|---|
| PubChem CID | 75535022 |
| InChIKey | GKXIUVNZWFPOHI-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H49N3O11/c1-24(2,3)38-23(29)27-26-22(28)4-6-30-8-10-32-12-14-34-16-18-36-20-21-37-19-17-35-15-13-33-11-9-31-7-5-25/h4-21,25H2,1-3H3,(H,26,28)(H,27,29) |
| SMILES | CC(C)(C)OC(=O)NNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe Amino-PEG8-t-Boc-hydrazide or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for Amino-PEG8-t-Boc-hydrazide be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0049 and CAS 1334169-96-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.