Cap Analogs
ARCA
Quick view. We supply ARCA as an anti-reverse cap analog for co-transcriptional mRNA capping. CAS 400806-46-4. Catalog target purity: Specification on request.

Product profile
ARCA is classified as rna cap analog or cap-related nucleotide (Formula C22H31N10O18P3; molecular weight 816.46).
ARCA can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For ARCA, capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
Names and search terms
Confirmed or normalized name variants
- m27.3'-OGP3G (ARCA Cap Analog)
Useful catalog search terms
- CAS 400806-46-4
- RNA cap analog or cap-related nucleotide
- Cap Analogs
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe ARCA or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for ARCA be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0001 and CAS 400806-46-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Cap Analogs product family and its named chemistry.
