Intermediates
DBCO-PEG2-acid
Quick view. DBCO-PEG2-acid is a DBCO PEG carboxylic-acid linker intermediate identified by CAS 2304558-25-4. CAS 2304558-25-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DBCO-PEG2-acid is classified as intermediates (Formula C26H28N2O6; molecular weight 464.51).
DBCO-PEG2-acid — Reference use: DBCO PEG linker studies involving strain-promoted azide-alkyne conjugation and carboxyl-group coupling.
For DBCO-PEG2-acid, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- DBCO-CONH-PEG2-CH2CH2COOH
- PrecisePEG AG-2131
Useful catalog search terms
- CAS 2304558-25-4
- C26H28N2O6
- IZLCAESRDHFGLF-UHFFFAOYSA-N
- PubChem CID 137700738
Physicochemical data
| Functional groups | DBCO and carboxylic acid |
|---|---|
| PubChem CID | 137700738 |
| InChIKey | IZLCAESRDHFGLF-UHFFFAOYSA-N |
| InChI | InChI=1S/C26H28N2O6/c29-24(27-14-16-34-18-17-33-15-13-26(31)32)11-12-25(30)28-19-22-7-2-1-5-20(22)9-10-21-6-3-4-8-23(21)28/h1-8H,11-19H2,(H,27,29)(H,31,32) |
| SMILES | C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCC(=O)NCCOCCOCCC(=O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe DBCO-PEG2-acid or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DBCO-PEG2-acid be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0051 and CAS 2304558-25-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.