Other Phosphoramidites
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Quick view. We supply di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) as a bifunctional MOE guanosine bis-amidite for branched, crosslinked or dimer-block oligonucleotide research. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Product profile
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) is classified as protected oligonucleotide phosphoramidite building block.
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite), mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- di(5'-O-DMT-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- 2'-O-MOE modification
- phosphoramidite coupling group
- Other Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; 2'-O-MOE modification; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0062, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry.