LNA Phosphoramidites
DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite as a benzoyl-protected LNA cytidine monomer for high-affinity oligo synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite, high-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite
- DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- conformationally locked sugar
- phosphoramidite coupling group
- LNA Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; conformationally locked sugar; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- Locked/bicyclic sugar motifs can substantially increase duplex thermal stability and mismatch discrimination.
Method limitations
- High-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
These points describe DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-2'-O-4'-C-Locked- rC(Ac)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: N/A
BX-LP-0002DMTr-2'-O-4'-C-Locked-5-Me-rC(Ac)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: N/A
BX-LP-0003DMTr-2'-O-4'-C-Locked-5-Me-rC(Bz)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-82-5
BX-LP-0004DMTr-2'-O-4'-C-Locked-rA(Bz)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-79-0
BX-LP-0006DMTr-2'-O-4'-C-Locked-rG(dmf)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 709641-79-2
BX-LP-0007DMTr-2'-O-4'-C-Locked-rG(iBu)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-77-8
Frequently asked questions
Can the package size for DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0005, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite or the named structural feature represented by this product.