DNA Phosphoramidites
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite
Quick view. We supply DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite as a modified DNA phosphoramidite for introducing functionalized or base-modified residues into synthetic oligonucleotides. CAS 1472616-97-9. Catalog target purity: Specification on request.
Product profile
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C50H67N4O8PSi; molecular weight 911.16).
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- DMT-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite
Useful catalog search terms
- CAS 1472616-97-9
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- alkyne click handle
- phosphoramidite coupling group
- DNA Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; alkyne click handle; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DP-0022 and CAS 1472616-97-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite or the named structural feature represented by this product.