DNA Phosphoramidites
DMTr-dC(Bz)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-dC(Bz)-3'-CE-Phosphoramidite as a protected DNA CE phosphoramidite for routine and modified solid-phase oligonucleotide synthesis. CAS 102212-98-6. Catalog target purity: Specification on request.
Product profile
DMTr-dC(Bz)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C46H52N5O8P; molecular weight 833.91).
DMTr-dC(Bz)-3'-CE-Phosphoramidite — 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
For DMTr-dC(Bz)-3'-CE-Phosphoramidite, reported solubility: Chloroform, DMSO, Methanol (Slightly). Storage: Sealed in dry,2-8°C.
Names and search terms
Confirmed or normalized name variants
- DMT-dC(bz) amidite
- DNAC-PHOSPHORAMIDITE
- Bz-dC Phosphoramidite
- DMT-dC-CEPhosphoramidite
- DMT-dC(bz) Phosphoramidite
- dC (N-Bz) Phosphoramidite
- 5'-DMT-Bz-dC phosphoramidite
- DMT-dC(Bz)-CE Phosphoramidite
Useful catalog search terms
- CAS 102212-98-6
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- phosphoramidite coupling group
- 2'-dC(Bz) Phosphoramidite
- BX-DP-0011
- DNA Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; phosphoramidite coupling group |
|---|---|
| Melting point | >84°C (dec.) |
| Density | 1.23 at 20℃ |
| Form | powder or granules |
| Color | white to off-white |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(=O)C3=CC=CC=C3)=NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,45,r| |
| InChIKey | PGTNFMKLGRFZDX-SALLYJDFSA-N |
| InChI | InChI=1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- DMTr-dC(Bz)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
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BX-DP-0003DMTr-3'-dG(iBu)-2'-CE-Phosphoramidite
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BX-DP-0004DMTr-5-Me-dC(C6-O-Lev)-3'-CE-Phosphoramidite
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BX-DP-0005DMTr-5-[N-(naphthalen-2-ylmethyl)formamide]-dU-3'-CE-Phosphoramidite
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BX-DP-0006DMTr-dA(dmf)-3'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for DMTr-dC(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DP-0028 and CAS 102212-98-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry.