Phosphorus Reagents
Methylenediphosphonic acid
Quick view. We supply Methylenediphosphonic acid as a methylenebis(phosphonate) or related phosphorus reagent for phosphate-mimic and medicinal chemistry workflows. CAS 1984-15-2. Catalog target purity: ≥98%.
Product profile
Methylenediphosphonic acid is classified as specialty phosphorus reagent or intermediate (Formula CH6O6P2; molecular weight 176).
Methylenediphosphonic acid can be used as a precursor in the synthesis of: Mesoporous aluminum organophosphonate in the presence of alkyltrimethylammonium as a surfactant. Tetraester of methylenediphosphonic acids which are used as metal ion extractants for actinides in all oxidation states.
For Methylenediphosphonic acid, reported solubility: DMSO: 250 mg/mL (1420.45 mM; Need ultrasonic). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- MDP
- MEDRONIC ACID
- METHYLENEBISPHOSPHONIC ACID
- PHOSPHONOMETHYLPHOSPHONIC ACID
- methylenediphosphonate
- METHYLENEDIPHOSPHONIC ACID FREE ACID
- MDP~Medronicacid
- Methanebisphosphonic Acid
Useful catalog search terms
- CAS 1984-15-2
- Specialty phosphorus reagent or intermediate
- Phosphorus Reagents
Physicochemical data
| Melting point | 197-199 °C(lit.) |
|---|---|
| Boiling point | 583.2±60.0 °C(Predicted) |
| Density | 2.111±0.06 g/cm3(Predicted) |
| pKa | 1.43±0.10(Predicted) |
| Form | Moist Crystals or Crystalline Powder |
| Color | Blue |
| SMILES | C(P(O)(O)=O)P(O)(O)=O |
| InChI | InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7) |
| InChIKey | MBKDYNNUVRNNRF-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Methylenediphosphonic acid can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
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Frequently asked questions
Can the package size for Methylenediphosphonic acid be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PR-0002 and CAS 1984-15-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.