Sulfurizing Reagents
Phenylacetyl Disulfide (PADS)
Quick view. A disulfide sulfurizing reagent used to convert nucleotide phosphite intermediates into phosphorothioates. CAS 15088-78-5. Catalog target purity: ≥97%.
Product profile
Phenylacetyl Disulfide (PADS) is classified as oligonucleotide sulfur-transfer reagent (Formula C16H14O2S2; molecular weight 302.41).
Phenylacetyl Disulfide (PADS) — Sulfurization during solid-phase preparation of phosphorothioate RNA and DNA.
For Phenylacetyl Disulfide (PADS), reported solubility: Chloroform (Slightly), Methanol (Slightly). Storage: Inert atmosphere,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- BIS(PHENYLACETYL) DISULFIDE
- BIS(PHENYLACETYL) DISULPHIDE
- PADS
- PHENYLACETYL DISULFIDE
- PHENYLACETYL DISULPHIDE
- DIPHENYLACETYL DISULFIDE
- PADS (PHENYLACETYL DISULFIDE)
Useful catalog search terms
- CAS 15088-78-5
- Oligonucleotide sulfur-transfer reagent
- sulfur/thiol functionality
- Sulfurizing Reagents
Physicochemical data
| Key chemistry motifs | sulfur/thiol functionality |
|---|---|
| Melting point | 59-63 °C (lit.) |
| Boiling point | 481.1±48.0 °C(Predicted) |
| Density | 1.269±0.06 g/cm3(Predicted) |
| Form | powder to crystal |
| Color | White to Almost white |
| SMILES | S(C(CC1=CC=CC=C1)=O)SC(CC1=CC=CC=C1)=O |
| InChI | InChI=1S/C16H14O2S2/c17-15(11-13-7-3-1-4-8-13)19-20-16(18)12-14-9-5-2-6-10-14/h1-10H,11-12H2 |
| InChIKey | IXGZXXBJSZISOO-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Development of activated PADS sulfurization systems for oligonucleotide synthesis.
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Frequently asked questions
Can the package size for Phenylacetyl Disulfide (PADS) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SR-0002 and CAS 15088-78-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Sulfurizing Reagents product family and its named chemistry.