BX Lab

BX LAB PRODUCT CATEGORY

Stereopure PS Reagents & Activators (PSI-ψ / CMPT)

Quick view. Stereocontrolled phosphorothioate synthesis reagents and activators, including PSI-ψ- and CMPT-type chemistry, for research-use oligonucleotide method development. This category currently includes 6 products. Stereopure PS reagents and activators support research into stereodefined phosphorothioate linkage formation and route evaluation in oligonucleotide synthesis.

Products6
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

Stereopure PS reagents and activators support research into stereodefined phosphorothioate linkage formation and route evaluation in oligonucleotide synthesis.

How to select

Confirm the reagent family, target backbone configuration, compatible activation and coupling conditions, solvent system, monomer set and sequence context.

How to qualify

Confirm identity, assay and stereochemical specification; control moisture and solution age; then verify conversion and stereochemical outcome on representative sequences.

Product-family considerations

Common advantages
  • Provides a dedicated category for PSI-ψ- and CMPT-type research workflows instead of mixing stereocontrolled PS chemistry with general sulfurizing reagents.
  • Supports method comparison around reagent family, activation conditions, sequence context and target phosphorothioate configuration.
Common limitations
  • Performance and stereochemical outcome are workflow-specific and require validation with the intended monomers, sequence, solvent system and synthesis platform.
  • Research-use material and method information do not replace product-specific specifications, handling controls or user qualification.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

6 products

N-(Cyanomethyl)pyrrolidinium Triflate (CMPT)

Specification on request · CAS: N/A

BX-PSR-0001
N-Phenylimidazolium Triflate (PhIMT)

Specification on request · CAS: N/A

BX-PSR-0002
Benzimidazolium Triflate (BIT)

Specification on request · CAS: N/A

BX-PSR-0003
4,5-Dicyanoimidazole (DCI)

≥97% · CAS: 1122-28-7

BX-CA-0035
1H-Tetrazole

Specification on request · CAS: 288-94-8

BX-PSR-0004
5-Benzylthio-1H-tetrazole (BTT)

≥98% · CAS: 21871-47-6

BX-CA-0036

Frequently asked questions

What are typical uses for Stereopure PS Reagents & Activators?

These reagents support research into stereodefined phosphorothioate linkage formation, method development and comparison of PSI-ψ- and CMPT-type workflows.

What should be confirmed before selecting a PSI-ψ- or CMPT-type reagent?

Confirm the target PS configuration, compatible activation and coupling conditions, monomer and sequence context, solvent requirements, reagent handling and analytical strategy.

Are product-specific quantities and specifications available?

BX Lab reviews research-use availability, specifications, pack sizes and related custom chemistry requests against the exact reagent, target workflow and project timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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