Sugars
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
Quick view. Cyclic D-ribitol derivative bearing a 2,4-difluorophenyl substituent at C1. CAS 263701-23-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is classified as sugars (Formula C11H12F2O4; molecular weight 246.21 g/mol).
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 1-Deoxy-1-(2,4-difluorophenyl)-beta-D-ribofuranose
Useful catalog search terms
- 263701-23-1
Physicochemical data
| PubChem CID | 91668173 |
|---|---|
| Systematic name | (2S,3R,4S,5R)-2-(2,4-difluorophenyl)-5-(hydroxymethyl)oxolane-3,4-diol |
| Chemical form | Neutral 1,4-anhydro-D-ribitol derivative |
| Structural scope | 2,4-Difluorophenyl substituent at sugar C1 |
| Stereochemical scope | Four defined sugar-ring stereocenters |
| InChIKey | PVOSUMDUOMMGTK-DBIOUOCHSA-N |
| InChI | InChI=1S/C11H12F2O4/c12-5-1-2-6(7(13)3-5)11-10(16)9(15)8(4-14)17-11/h1-3,8-11,14-16H,4H2/t8-,9-,10-,11+/m1/s1 |
| SMILES | C1=CC(=C(C=C1F)F)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-SUGA-0011Lactose (Gal-beta-1,4-Glc)
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BX-SUGA-0012Maltose Monohydrate (Glc-alpha-1,4-Glc)
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BX-SUGA-0013Isomaltose (Glc-alpha-1,6-Glc)
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BX-SUGA-0014Lactulose (Gal-beta-1,4-Fru)
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Frequently asked questions
Can the package size for (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUGA-0086 and CAS 263701-23-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Technology platforms
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