Modified Nucleosides
2',3'-Didehydro-2',3'-dideoxythymidine
Quick view. A stereodefined 2',3'-didehydro-2',3'-dideoxy thymidine analog, also known as stavudine or d4T, CAS 3056-17-5. CAS 3056-17-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Didehydro-2',3'-dideoxythymidine is classified as modified nucleosides (Formula C10H12N2O4; molecular weight 224.21 g/mol).
2',3'-Didehydro-2',3'-dideoxythymidine — Didehydro-dideoxy thymidine analog for modified nucleoside chemistry.
For 2',3'-Didehydro-2',3'-dideoxythymidine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Stavudine
- d4T
- 2',3'-Dideoxy-2',3'-didehydrothymidine
Useful catalog search terms
- 3056-17-5
- PubChem CID 18283
- XNKLLVCARDGLGL-JGVFFNPUSA-N
Physicochemical data
| PubChem CID | 18283 |
|---|---|
| IUPAC name | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione |
| InChIKey | XNKLLVCARDGLGL-JGVFFNPUSA-N |
| InChI | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO |
| Stereochemistry | (2R,5S) dihydrofuran nucleoside system |
| Nucleoside modification | 2',3'-didehydro and 2',3'-dideoxy |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Reference compound for chemical identity studies involving stavudine (d4T).
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Didehydro-2',3'-dideoxythymidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Didehydro-2',3'-dideoxythymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0478 and CAS 3056-17-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.