Modified Nucleosides
2',5'-Bis-O-(triphenylmethyl)uridine
Quick view. We supply 2',5'-Bis-O-(triphenylmethyl)uridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 6554-11-6. Catalog target purity: Specification on request.
Product profile
2',5'-Bis-O-(triphenylmethyl)uridine is classified as nucleoside or protected nucleoside intermediate (Formula C47H40N2O6; molecular weight 728.83).
2',5'-Bis-O-(triphenylmethyl)uridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',5'-Bis-O-(triphenylmethyl)uridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 1-[2,5-Bis-O-(triphenylmethyl)pentofuranosyl]-4-hydroxypyrimidin-2(1H)-one
- NSC 94674
- 2',5'-Ditrityluridine
- 2',5'-di-O-trityluridine
- 2',5'-O-Bis(triphenylmethyl)uridine
Useful catalog search terms
- CAS 6554-11-6
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C47H40N2O6/c50-41-31-32-49(45(52)48-41)44-43(55-47(37-25-13-4-14-26-37,38-27-15-5-16-28-38)39-29-17-6-18-30-39)42(51)40(54-44)33-53-46(34-19-7-1-8-20-34,35-21-9-2-10-22-35)36-23-11-3-12-24-36/h1-32,40,42-44,51H,33H2,(H,48,50,52) |
|---|---|
| InChIKey | DHKUAWARIDEGPI-UHFFFAOYSA-N |
| SMILES | O=c1nc(O)ccn1C1OC(COC(c2ccccc2)(c2ccccc2)c2ccccc2)C(O)C1OC(c1ccccc1)(c1ccccc1)c1ccccc |
| Melting point | 215-220 °C |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2',5'-Bis-O-(triphenylmethyl)uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0624 and CAS 6554-11-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.