Amino-modified Nucleosides
2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine
Quick view. We supply 2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 4546-70-7. Catalog target purity: Specification on request.
Product profile
2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O3; molecular weight 266.26).
2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine, reported solubility: DMSO (Slightly, Heated), Methanol (slightly, Heated), Water (Slightly, Sonicated). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 2,6-Diaminopurine 2'-deoxyriboside
- Nsc104303
- 2-NH2-2'-dA
- 2-amino-2’-deoxy-adenosin
- 2'-Deoxy-2-aminoadenosine
- 2-AMino-2'-desoxyadenosine
- 2,6-Diaminopurine Deoxyribose
- 2,6-diaminopurinedeoxyriboside
Useful catalog search terms
- CAS 4546-70-7
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H14N6O3/c11-8-7-9(15-10(12)14-8)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H4,11,12,14,15)/t4-,5+,6+/m0/s |
| InChIKey | NOLHIMIFXOBLFF-KVQBGUIXSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)C[C@@H]1O |
| Melting point | 144°C |
| Boiling point | 748.4±70.0 °C(Predicted) |
| Density | 2.08±0.1 g/cm3(Predicted) |
| pKa | 13.79±0.60(Predicted) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2,6-Diaminopurine-2’-deoxyriboside is a nucleoside analogs synthesized to interfere with DNA metabolism. A derivative of 2,6-Diaminopurine, which can be used as analyte for biological and analytical studies of incorporation of unnatural nucleotides into mutant tRNA and proteins.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2,6-Diamino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0084 and CAS 4546-70-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.