Amino-modified Nucleosides
2'-Azido-2'-deoxyuridine
Quick view. We supply 2'-Azido-2'-deoxyuridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 26929-65-7. Catalog target purity: Specification on request.
Product profile
2'-Azido-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11N5O5; molecular weight 269.21).
2'-Azido-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Azido-2'-deoxyuridine, storage: 2-8°C. Form: powder to crystal.
Names and search terms
Confirmed or normalized name variants
- N3-dU
- N3dUrd
- 2'-Az-dU
- 2'-N3-2'-dU
- 2''-AZIDO-D-URIDINE
- Uridine,2'-azido-2'-deoxy-
- 2'-Azido-2'-deoxy-D-uridine
- 2'-Azido-2'-deoxyuridine USP/EP/BP
Useful catalog search terms
- CAS 26929-65-7
- Nucleoside or protected nucleoside intermediate
- azide click handle
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | azide click handle; amine functionality |
|---|---|
| InChI | InChI=1S/C9H11N5O5/c10-13-12-6-7(17)4(3-15)19-8(6)14-2-1-5(16)11-9(14)18/h1-2,4,6-8,15,17H,3H2,(H,11,16,18) |
| InChIKey | MRUKYOQQKHNMFI-UHFFFAOYSA-N |
| SMILES | [N-]=[N+]=NC1C(O)C(CO)OC1n1ccc(O)nc1=O |
| Melting point | 149-153 °C |
| Form | powder to crystal |
| Color | White to Almost white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Azido-2'-deoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Azido-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0196 and CAS 26929-65-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-Azido-2'-deoxyuridine or the named structural feature represented by this product.