2'-FANA Nucleosides
2'-FANA-dG
Quick view. We supply 2'-FANA-dG as a 2'-fluoro-arabino guanosine nucleoside for FANA oligonucleotide and nucleotide analog research. CAS 103884-98-6. Catalog target purity: Specification on request.
Product profile
2'-FANA-dG is classified as nucleoside or protected nucleoside intermediate (Formula C10H12FN5O4; molecular weight 285.23).
2'-FANA-dG can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-FANA-dG, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2’-Deoxy-2’-fluoro-β-D-arabinoguanosine
- 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
- 9-(2-deoxy-2-fluoroarabinofuranosyl)guanine
- 2'-Fluoro-2'-deoxy-arabinofuranosyl-guanosine
- 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)guanine
- 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
- 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin
- 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine
Useful catalog search terms
- CAS 103884-98-6
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| Melting point | 275-279 °C |
| Boiling point | 726.1±70.0 °C(Predicted) |
| Density | 2.17±0.1 g/cm3(Predicted) |
| pKa | 12.68±0.70(Predicted) |
| SMILES | C12N=C(NC(=O)C=1N=CN2[C@H]1[C@@H](F)[C@H](O)[C@@H](CO)O1)N |&1:10,11,13,15,r| |
| InChI | InChI=1/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9-/s |
| InChIKey | UXUZARPLRQRNNX-DUDCECJTNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-FANA-dG or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-FANA-dA
2'-FANA Nucleosides · CAS: 20227-41-2
BX-MN-01622'-FANA-dC
2'-FANA Nucleosides · CAS: 56632-83-8
BX-MN-01632'-FANA-dT
2'-FANA Nucleosides · CAS: 69256-17-3
BX-MN-01722'-FANA-dU
2'-FANA Nucleosides · CAS: 69123-94-0
BX-2FAN-00012'-Deoxy-2'-fluoro-beta-D-arabino-2-thiouridine
2'-FANA Nucleosides · CAS: 1006872-85-0
BX-2FAN-00023',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabino-6-azidouridine
2'-FANA Nucleosides · CAS: 1013470-68-2
Frequently asked questions
Can the package size for 2'-FANA-dG be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0160 and CAS 103884-98-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-FANA-dG or the named structural feature represented by this product.