Amino-modified Nucleosides
2-Hydrazinoadenosine
Quick view. We supply 2-Hydrazinoadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 15763-11-8. Catalog target purity: Specification on request.
Product profile
2-Hydrazinoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H15N7O4; molecular weight 297.27).
2-Hydrazinoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Hydrazinoadenosine, storage: -20?C Freezer.
Names and search terms
Confirmed or normalized name variants
- (2R,3R,4S,5R)-2-(6-amino-2-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- BINO-006
- 2-Hydrazinyl-adenosine
- Adenosine, 2-hydrazinyl-
Useful catalog search terms
- CAS 15763-11-8
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H15N7O4/c11-7-4-8(15-10(14-7)16-12)17(2-13-4)9-6(20)5(19)3(1-18)21-9/h2-3,5-6,9,18-20H,1,12H2,(H3,11,14,15,16)/t3-,5-,6-,9-/m1/s |
| InChIKey | BAYFDGKAUSOEIS-UUOKFMHZSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)NN)N |
| Melting point | 208-210°C |
| Boiling point | 583.1±60.0 °C(Predicted) |
| Density | 2.29±0.1 g/cm3(Predicted) |
| pKa | 12.76±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2-Hydrazinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Hydrazinoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0145 and CAS 15763-11-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.