Modified Nucleosides
2-Methyladenosine
Quick view. We supply 2-Methyladenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 16526-56-0. Catalog target purity: Specification on request.
Product profile
2-Methyladenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O4; molecular weight 281.27).
2-Methyladenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Methyladenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N2-Me-Adenosine
- C2-Methyladenosine
- Adenosine, 2-Methyl-
- 2-Methyladenosine,RNA-modified nucleoside m2A
Useful catalog search terms
- CAS 16526-56-0
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H15N5O4/c1-4-14-9(12)6-10(15-4)16(3-13-6)11-8(19)7(18)5(2-17)20-11/h,5,7-8,11,17-19H,2H2,1H3,(H2,12,14,15)/t5-,7-,8-,11-/m1/s |
|---|---|
| InChIKey | IQZWKGWOBPJWMX-IOSLPCCCSA-N |
| SMILES | Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n |
| Boiling point | 517.8±60.0 °C(Predicted) |
| Density | 1.96±0.1 g/cm3(Predicted) |
| pKa | 13.12±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2-Methyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0280 and CAS 16526-56-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.