Modified Nucleotides
2'-O-4'-C-Locked-m7GMP Sodium Salt
Quick view. A sodium salt of N7-methyl LNA-GMP, with a 2'-O,4'-C methylene bridge in the sugar and a 5'-monophosphate group. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-4'-C-Locked-m7GMP Sodium Salt is classified as modified nucleotides.
2'-O-4'-C-Locked-m7GMP Sodium Salt supports in-vitro transcription and capped RNA preparation, including mRNA research and translation studies.
For 2'-O-4'-C-Locked-m7GMP Sodium Salt, capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
Names and search terms
Confirmed or normalized name variants
- LNA-m7GMP Sodium Salt
Physicochemical data
| Salt form | Sodium salt |
|---|---|
| Counterion stoichiometry | Not specified |
| Base modification | N7-methyl guanine |
| Sugar modification | 2'-O,4'-C methylene bridge |
| Hydroxyl state | One sugar hydroxyl unprotected |
| Phosphate state | 5'-monophosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe 2'-O-4'-C-Locked-m7GMP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-O-4'-C-Locked-m7GMP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0031, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.