Modified Nucleosides
2-Thiocytidine
Quick view. We supply 2-Thiocytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 13239-97-9. Catalog target purity: Specification on request.
Product profile
2-Thiocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H13N3O4S; molecular weight 259.28).
2-Thiocytidine (CAS# 13239-97-9) is a cytidine analogue. A profiled metabolite in HFD-induced obese mice after oral administration of Huangjinya green tea extract.
For 2-Thiocytidine, reported solubility: Methanol (Slightly), Water (Slightly). Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere.
Names and search terms
Confirmed or normalized name variants
- Einecs 236-214-8
- Cytidine, 2-thio-
- 2-THIOCYTIDINE USP/EP/BP
- 2-THIOCYTIDINE DIHYDRATE
- 1-(β-D-Ribofuranosyl)-4-aminopyrimidine-2(1H)-thione
Useful catalog search terms
- CAS 13239-97-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H13N3O4S/c10-5-1-2-12(9(17)11-5)8-7(15)6(14)4(3-13)16-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,17)/t4-,6-,7-,8-/m1/s |
|---|---|
| InChIKey | RHFUOMFWUGWKKO-XVFCMESISA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=S)[C@H](O)[C@@H]1O |
| Melting point | 208-209 °C |
| Boiling point | 540.5±60.0 °C(Predicted) |
| Density | 1.85±0.1 g/cm3(Predicted) |
| pKa | 12.97±0.70(Predicted) |
| Form | Solid |
| Color | Off-White to Dark Brown |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2-Thiocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2-Thiocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0235 and CAS 13239-97-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.