Modified Nucleotides
3'-O-Methylguanosine 5'-triphosphate, Tris salt
Quick view. The Tris salt form of a guanosine 5'-triphosphate bearing a methyl substituent on the ribose 3'-oxygen. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-O-Methylguanosine 5'-triphosphate, Tris salt is classified as 3'-o-methyl guanosine 5'-triphosphate.
3'-O-Methylguanosine 5'-triphosphate, Tris salt can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-O-Methylguanosine 5'-triphosphate, Tris salt, form: Tris salt.
Names and search terms
Confirmed or normalized name variants
- 3'-OMe GTP
- 3'-Methoxy-guanosine 5'-triphosphate, Tris salt
Useful catalog search terms
- 61556-45-4 free acid
Physicochemical data
| Molecular formula (free acid) | C11H18N5O14P3 |
|---|---|
| Molecular weight (free acid) | 537.21 g/mol |
| Free-acid reference CAS | 61556-45-4 |
| Form | Tris salt |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-O-Methylguanosine 5'-triphosphate, Tris salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-O-Methylguanosine 5'-triphosphate, Tris salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MODN-0243, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.