ddNTPs
3'-NH₂-ddTTP Sodium Salt
Quick view. We supply 3'-NH₂-ddTTP Sodium Salt as a 3'-amino dideoxy nucleotide analog for chain-termination and sequencing-chemistry research. CAS 90053-16-0. Catalog target purity: ≥98%.
Product profile
3'-NH₂-ddTTP Sodium Salt is classified as specialty research-use chemical building block (Formula C10H18N3O13P3; molecular weight 481.18 g/mol (calculated from molecular formula)).
3'-NH₂-ddTTP Sodium Salt can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
For 3'-NH₂-ddTTP Sodium Salt, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 3'-Deoxy-3'-aminothymidine-5'triphosphate
Useful catalog search terms
- CAS 90053-16-0
- Specialty research-use chemical building block
- ddNTPs
Physicochemical data
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
|---|---|
| InChI | InChI=1S/C10H18N3O13P3/c1-5-3-13(10(15)12-9(5)14)8-2-6(11)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18/h,6-8H,2,4,11H2,1H3,(H,19,20)(H,21,22)(H,12,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s |
| InChIKey | FGYGYHFEBIMMKO-XLPZGREQSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 3'-NH₂-ddTTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-NH₂-ddTTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DDNT-0004 and CAS 90053-16-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the ddNTPs product family and its named chemistry.