Reverse Phosphoramidites
3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite
Quick view. We supply 3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite as a reverse thymidine amidite for inverted DNA oligonucleotide synthesis. CAS 134031-86-0. Catalog target purity: ≥98%.
Product profile
3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C40H49N4O9P; molecular weight 760.81).
3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For 3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite, reported solubility: DMSO: Sparingly soluble: 1-10 mg/ml Ethanol: Sparingly soluble: 1-10 mg/ml. Storage: under inert gas (nitrogen or Argon) at 2-8°C.
Names and search terms
Confirmed or normalized name variants
- Rev T-5’-amidite
- 2'-OMe-U Phosphoramidite
- 2'-OMe-rU-CE Phosphoramidite
- DMT-dT-CE Reverse Phosphoramidite
- DMT-dT-5'-CE Reverse Phosphoramidite
- 3'-O-DMT-thymidine 5'-CE phosphoramidite
- 3’-O-DMTr-thymidine 5’-CE phosphoramidite
- 2'-O-Methyl-5'-O-DMT-Uridine-3'-CE-Phosphoramidite
Useful catalog search terms
- CAS 134031-86-0
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- phosphoramidite coupling group
- Reverse Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; phosphoramidite coupling group |
|---|---|
| InChI | InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(47,50-23-11-22-41)51-26-36-35(24-37(52-36)43-25-29(5)38(45)42-39(43)46)53-40(30-12-9-8-10-13-30,31-14-18-33(48-6)19-15-31)32-16-20-34(49-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,54?/m0/s |
| InChIKey | BEMDXQXSHVUENL-JYQXRUAGSA-N |
| SMILES | COc1ccc(C(O[C@H]2C[C@H](n3cc(C)c(O)nc3=O)O[C@@H]2COP(=O)(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Related products
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BX-RP-00053'-O-DMTr-2'-O-MOE-rT-5'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for 3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-RP-0008 and CAS 134031-86-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Reverse Phosphoramidites product family and its named chemistry.