Modified Nucleotides
3'-OMe-GDP TEA Salt
Quick view. We supply 3'-OMe-GDP TEA Salt as the triethylammonium salt form of 3'-O-methyl GDP, used as a cap-intermediate precursor and analytical reference for ARCA-like nucleotide chemistry. CAS 78771-34-3. Catalog target purity: ≥95%.
Product profile
3'-OMe-GDP TEA Salt is classified as nucleoside diphosphate or analog (Formula C11H17N5O11P2; molecular weight 457.23).
3'-OMe-GDP TEA Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 3'-OMe-GDP TEA Salt, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- 3'-O-methylguanosine 5'-diphosphate
- Guanosine 5'-(trihydrogen diphosphate), 3'-O-methyl- (9CI)
- Guanosine 5′-(trihydrogen diphosphate), 3′-O-methyl-
Useful catalog search terms
- CAS 78771-34-3
- Nucleoside diphosphate or analog
- Modified Nucleotides
Physicochemical data
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
|---|---|
| Boiling point | 906.0±75.0 °C(Predicted) |
| Density | 2.37±0.1 g/cm3(Predicted) |
| pKa | 1.04±0.50(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-OMe-GDP TEA Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-OMe-GDP TEA Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0034 and CAS 78771-34-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.