Modified Nucleosides
4',5'-Didehydro-5'-deoxyadenosine
Quick view. We supply 4',5'-Didehydro-5'-deoxyadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 20535-04-0. Catalog target purity: Specification on request.
Product profile
4',5'-Didehydro-5'-deoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H11N5O3; molecular weight 249.23).
4',5'-Didehydro-5'-deoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 4',5'-Didehydro-5'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 9-(5-deoxypent-4-enofuranosyl)-9h-purin-6-amine
- CALCIUM BIS(CYCLOHEXYLSULFAMATE)
- Adenosine, 4',5'-didehydro-5'-deoxy-
- 4’,5’-Didehydro-5’-deoxyadenosine, 1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)adenine
Useful catalog search terms
- CAS 20535-04-0
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H11N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-3,6-7,10,16-17H,1H2,(H2,11,12,13) |
|---|---|
| InChIKey | OGHMFWYXBZGWRH-UHFFFAOYSA-N |
| SMILES | C=C1OC(n2cnc3c(N)ncnc32)C(O)C1O |
| Melting point | 195-196 °C (decomp)(Solv: methanol (67-56-1); acetone (67-64-1)) |
| Boiling point | 591.1±60.0 °C(Predicted) |
| Density | 1.91±0.1 g/cm3(Predicted) |
| pKa | 13.15±0.60(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 4',5'-Didehydro-5'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0341 and CAS 20535-04-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.