Modified Nucleosides
5-Aza-2'-deoxycytidine
Quick view. We supply 5-Aza-2'-deoxycytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2353-33-5. Catalog target purity: Specification on request.
Product profile
5-Aza-2'-deoxycytidine is classified as nucleoside or protected nucleoside intermediate (Formula C8H12N4O4; molecular weight 228.21).
5-Aza-2'-deoxycytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Aza-2'-deoxycytidine, reported solubility: acetic acid/water (1:1): 50 mg/mL. Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- decitabine
- 2'-DEOXY-5-AZACYTIDINE
- 4-AMINO-1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-1,3,5-TRIAZIN-2(1H)-ONE
- 5-AZA-CDR
- 5-AZA-DC
- 5-DEOXY-2'-AZACYTIDINE
- 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on
- 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one
Useful catalog search terms
- CAS 2353-33-5
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s |
|---|---|
| InChIKey | XAUDJQYHKZQPEU-KVQBGUIXSA-N |
| SMILES | NC1=NC(=O)N(C=N1)[C@H]2C[C@H](O)[C@@H](CO)O2 |
| Melting point | ~200 °C (dec.) |
| Boiling point | 370.01°C (rough estimate) |
| Density | 1.3771 (rough estimate) |
| pKa | 14.02±0.60(Predicted) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Aza-2'-deoxycytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0406 and CAS 2353-33-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.