Modified Nucleosides
5-(Carbonyl)methyluridine
Quick view. We supply 5-(Carbonyl)methyluridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 20964-06-1. Catalog target purity: Specification on request.
Product profile
5-(Carbonyl)methyluridine is classified as nucleoside or protected nucleoside intermediate (Formula C11H14N2O8; molecular weight 302.24).
5-(Carbonyl)methyluridine — 5-Uridineacetic Acid is a uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA).
For 5-(Carbonyl)methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5-(carboxymethyl)uridine
- 5-Uridineacetic acid
- 5-(Carbonyl)methyluridine, Uridine-5-acetic acid
- 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-
- 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic acid
- 5-(Carbonyl)methyluridine,Uridine-5-acetic acid, RNA-modified nucleoside cm5U
Useful catalog search terms
- CAS 20964-06-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H14N2O8/c14-3-5-7(17)8(18)10(21-5)13-2-4(1-6(15)16)9(19)12-11(13)20/h,5,7-8,10,14,17-18H,1,3H2,(H,15,16)(H,12,19,20)/t5-,7-,8-,10-/m1/s |
|---|---|
| InChIKey | FAWQJBLSWXIJLA-VPCXQMTMSA-N |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CC(=O)O |
| Density | 1.717±0.06 g/cm3(Predicted) |
| pKa | 3.86±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-(Carbonyl)methyluridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-(Carbonyl)methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0366 and CAS 20964-06-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.