DMTr-protected Nucleosides
5'-O-DMTr-2'-F-dC(Bz)
Quick view. We supply 5'-O-DMTr-2'-F-dC(Bz) as a 5'-DMT, N4-benzoyl protected 2'-fluoro cytidine/deoxycytidine intermediate for preparing 2'-F cytidine phosphoramidites and modified RNA building blocks. CAS is listed as N/A. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Product profile
5'-O-DMTr-2'-F-dC(Bz) is classified as nucleoside or protected nucleoside intermediate.
5'-O-DMTr-2'-F-dC(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-2'-F-dC(Bz), coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-2'-F-dC(Bz)
Useful catalog search terms
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- 2'-fluoro modification
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; 2'-fluoro modification |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5'-O-DMTr-2'-F-dC(Bz) or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-F-dC(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0026, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.