Protected Nucleosides
5'-O-DMTr-Inosine
Quick view. We supply 5'-O-DMTr-Inosine as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 119898-59-8. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-O-DMTr-Inosine is classified as nucleoside or protected nucleoside intermediate (Formula C31H30N4O7; molecular weight 570.59).
5'-O-DMTr-Inosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-Inosine, reported solubility: DMSO: 250 mg/mL (438.14 mM; Need ultrasonic). Storage: 4°C, protect from light.
Names and search terms
Confirmed or normalized name variants
- DMT-Ir
- 5'-O-DMT-rI
- 5'-O-DMT-inosine
- 5''-O-(4,4''-Dimethoxytrityl)-inosine
- 5''-O-(4,4''-Dimethoxytrityl)-inosine USP/EP/BP
- Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (9CI)
Useful catalog search terms
- CAS 119898-59-8
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- Protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5'-O-DMT-Ri can be used in the synthesis of oligoribonucleotides.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-DMTr-Inosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0136 and CAS 119898-59-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.