Modified Nucleosides
6-SH-deoxyguanosine
Quick view. We supply 6-SH-deoxyguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 789-61-7. Catalog target purity: Specification on request.
Product profile
6-SH-deoxyguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13N5O3S; molecular weight 283.31).
6-SH-deoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 6-SH-deoxyguanosine, reported solubility: DMSO (Slightly), DMF (Slightly), Methanol (Slightly, Heated), Water (Very Slightly). Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere.
Names and search terms
Confirmed or normalized name variants
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
- tgdr
- 6-SH-dG
- 6-Thio-dG
- NSC-71261
- Aids010571
- nci-c01581
- Thiodeoxyguanosine
Useful catalog search terms
- CAS 789-61-7
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s |
|---|---|
| InChIKey | SCVJRXQHFJXZFZ-HSUXUTPPSA-N |
| SMILES | S=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1 |
| Melting point | 190-192 °C |
| Boiling point | 709.1±70.0 °C(Predicted) |
| Density | 2.02±0.1 g/cm3(Predicted) |
| pKa | 6.81±0.20(Predicted) |
| Form | Solid |
| Color | Yellow to Brown |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 6-SH-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0673 and CAS 789-61-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.