Halogenated Nucleosides
8-Cl-2'-dA
Quick view. We supply 8-Cl-2'-dA as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 85562-55-6. Catalog target purity: ≥98%.
Product profile
8-Cl-2'-dA is classified as nucleoside or protected nucleoside intermediate (Formula C10H12ClN5O3; molecular weight 285.69).
8-Cl-2'-dA can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Cl-2'-dA, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 8-CL-DADO
- 8-CHLORO-2'-DEOXYADENOSINE
- 8-Chloro-2'-deoxy-D-adenosine
- Adenosine, 8-chloro-2'-deoxy-
- 8-Chloro-9-(2-deoxypentofuranosyl)-9H-purin-6-amine
Useful catalog search terms
- CAS 85562-55-6
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| Boiling point | 660.0±65.0 °C(Predicted) |
|---|---|
| Density | 2.03±0.1 g/cm3(Predicted) |
| pKa | 13.65±0.60(Predicted) |
| InChI | InChI=1S/C10H12ClN5O3/c11-10-15-7-8(12)13-3-14-9(7)16(10)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,13,14) |
| InChIKey | CHQZLVMNWNFWCR-UHFFFAOYSA-N |
| SMILES | Nc1ncnc2c1nc(Cl)n2C1CC(O)C(CO)O1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Cl-2'-dA be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0003 and CAS 85562-55-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.