Modified Nucleotides
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt
Quick view. A monosodium NAD+ analog bearing a 2'-deoxy-2'-fluoro-arabino modification on the nicotinamide-linked sugar. The adenine-linked ribose and pyrophosphate linkage remain present. CAS 133575-27-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt is classified as modified nucleotides (Formula C21H25FN7NaO13P2; molecular weight 687.40).
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- Ara-F-NAD+ Sodium Salt
- beta-Ara-2'-F-NAD+ Sodium Salt
- beta-Ara-2'-Deoxy-2'-Fluoro-NAD+ Sodium Salt
Useful catalog search terms
- CAS 133575-27-6
Physicochemical data
| Salt form | Monosodium salt |
|---|---|
| Modification | 2'-deoxy-2'-fluoro-arabino substitution on the nicotinamide-linked sugar |
| Related parent PubChem CID | 44238635 |
| Related parent InChIKey | JSGNSBZQCQQLEF-OZCXFSBSSA-N |
| Dinucleotide linkage | Pyrophosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0097 and CAS 133575-27-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
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