Cap Analogs
CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt
Quick view. We supply CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt as a TNA-modified m7G cap analog for mRNA cap sugar-replacement SAR. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt is classified as rna cap analog or cap-related nucleotide.
CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Useful catalog search terms
- RNA cap analog or cap-related nucleotide
- 2'-O-methyl modification
- Cap Analogs
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA
Cap Analogs · CAS: 400806-46-4
BX-CA-0002CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0003CAP 4 m7G(UNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0004CAP 5 m7G(5')vppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 2645354-92-1
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for CAP 12 m7G(TNA)ppp(5')(2'-OMeA)pG Ammonium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CAP-0038, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Cap Analogs product family and its named chemistry.