2'-Fluoro Phosphoramidites
DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite
Quick view. A stereodefined 5'-C-methyl, 2'-fluoro dA(Bz) CE phosphoramidite building block for research-use oligonucleotide synthesis. CAS 3055727-89-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite is classified as protected s-5-c-methyl 2'-fluoro da(bz) ce phosphoramidite (Formula C48H53FN7O7P; molecular weight 889.90).
DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite — This protected phosphoramidite is cataloged as a building block for research-use oligonucleotide synthesis.
For DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- CAS 3055727-89-1
- PubChem CID 177788755
- C48H53FN7O7P
- DMT-S-5-C-Me-2'-F-dA(Bz)-3'-CE phosphoramidite
Physicochemical data
| PubChem CID | 177788755 |
|---|---|
| InChIKey | MDSLUQNCOVDOHF-RQONQVHKSA-N |
| Nucleobase protection | N6-benzoyl (Bz) |
| Sugar modification | 2'-fluoro and stereodefined 5'-C-methyl |
| 3'-function | 2-cyanoethyl N,N-diisopropyl phosphoramidite |
| Phosphorus stereochemistry | Unspecified |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0012 and CAS 3055727-89-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.