GalNAc
GalNAc-THA8 Phosphoramidite
Quick view. We supply GalNAc-THA8 Phosphoramidite as a THA/C6-type tri-GalNAc phosphoramidite for synthesizing ASGPR-targeted oligonucleotide conjugates. CAS 2058062-52-3. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
GalNAc-THA8 Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
GalNAc-THA8 Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For GalNAc-THA8 Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Useful catalog search terms
- CAS 2058062-52-3
- Protected oligonucleotide phosphoramidite building block
- GalNAc ligand motif
- phosphoramidite coupling group
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe GalNAc-THA8 Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for GalNAc-THA8 Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0043 and CAS 2058062-52-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss GalNAc-THA8 Phosphoramidite or the named structural feature represented by this product.