2'-Fluoro Phosphoramidites
N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite
Quick view. We supply N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite as a specialty phosphoramidite building block for solid-phase oligonucleotide synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- 2'-fluoro modification
- phosphoramidite coupling group
- 2'-Fluoro Phosphoramidites
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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2'-Fluoro Phosphoramidites · CAS: N/A
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BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
Frequently asked questions
Can the package size for N2-acetyl -5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyguanosine-3'-cyanoethyl Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0034, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry.