Modified Nucleosides
N2-Ethylguanosine
Quick view. We supply N2-Ethylguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 77312-39-1. Catalog target purity: Specification on request.
Product profile
N2-Ethylguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C12H17N5O5; molecular weight 311.29).
N2-Ethylguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N2-Ethylguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N-Ethylguanosine
- Guanosine, N-ethyl-
Useful catalog search terms
- CAS 77312-39-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C12H17N5O5/c1-2-13-12-15-9-6(10(21)16-12)14-4-17(9)11-8(20)7(19)5(3-18)22-11/h4-5,7-8,11,18-20H,2-3H2,1H3,(H2,13,15,16,21)/t5-,7-,8-,11-/m1/s |
|---|---|
| InChIKey | NNQCGMWOZJYFTM-IOSLPCCCSA-N |
| SMILES | CCN=c1nc(O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2[nH]1 |
| Melting point | 237-239 °C (decomp) |
| Density | 1.89±0.1 g/cm3(Predicted) |
| pKa | 10.86±0.20(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N2-Ethylguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0672 and CAS 77312-39-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.