Base-protected Nucleosides
rC(Ac)
Quick view. We supply rC(Ac) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 3768-18-1. Catalog target purity: Specification on request.
Product profile
rC(Ac) is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N3O6; molecular weight 285.25).
rC(Ac) — N4-Acetylcytidine (cas# 3768-18-1) is a nucleotide-derived metabolite used as biomarkers for diagnosis of inflammation-related diseases.
For rC(Ac), reported solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 4-Acetyl-1-(beta-D-ribofuranosyl)cytosine
- ACETYL CYTOSINE
- N4-ACETYLCYTIDINE
- 4-Acetylcytidine
- Acetamide, N-(1,2-dihydro-2-oxo-1-beta-D-ribofuranosyl-4-pyrimidinyl)-
- Acetylcytidine
- n-acetyl-cytidin
- N-Acetylcytidine
Useful catalog search terms
- CAS 3768-18-1
- Nucleoside or protected nucleoside intermediate
- Base-protected Nucleosides
Physicochemical data
| Melting point | 199 °C (dec.)(lit.) |
|---|---|
| Density | 1.72±0.1 g/cm3(Predicted) |
| pKa | 10.21±0.20(Predicted) |
| Form | Solid |
| Color | White to Pale Yellow |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(NC(C)=O)=NC2=O)[C@H](O)[C@@H]1O |
| InChI | InChI=1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s |
| InChIKey | NIDVTARKFBZMOT-PEBGCTIMSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- rC(Ac) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
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Frequently asked questions
Can the package size for rC(Ac) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0091 and CAS 3768-18-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry.